A new class of antibiotics has been discovered 2016. Just by analysing
the bacterial warfare taking place up people's noses. As any technician could say how has this been over look, in health nutrition.
Tests reported in the Journal of Nature found the resulting drug, lugdunin', could treat MRSA infection. The researchers, at the University of Tubingen in Germany, say the human body is an untapped source of new drugs. The last new class of the drugs to reach patients was discovered in the 1980s. Nearly all antibiotics were discovered in soil bacteria, but the University of Tubingen research team turned to the battlefield, to put on a microscopic level a struggle. This space for food is taking place between rival species of bacteria. One of the weapons they have long been suspected of using is antibiotics. Among the bugs that like to invade the nose is Staphylococcus aureus, including the dreaded super-bug strain MRSA. It is found in the noses of 30% of people. About 30% of humans carry this Staphylococcus.
Tests reported in the Journal of Nature found the resulting drug, lugdunin', could treat MRSA infection. The researchers, at the University of Tubingen in Germany, say the human body is an untapped source of new drugs. The last new class of the drugs to reach patients was discovered in the 1980s. Nearly all antibiotics were discovered in soil bacteria, but the University of Tubingen research team turned to the battlefield, to put on a microscopic level a struggle. This space for food is taking place between rival species of bacteria. One of the weapons they have long been suspected of using is antibiotics. Among the bugs that like to invade the nose is Staphylococcus aureus, including the dreaded super-bug strain MRSA. It is found in the noses of 30% of people. About 30% of humans carry this Staphylococcus.
The scientists discovered that
people with the rival bug Staphylococcus lugdunensis in their nostrils were
less likely to have Sinus. The German team used various strains of
genetically-modified S. lugdunensis to work out the crucial piece of genetic
code that allowed it to win the fight to live. where they eventually pinpointed a single
instructions for building a new antibiotic,Tests on mice showed lugdunin could
treat superbug infections on the skin including MRSA, as well as Enterococcus.
One of the researchers, Dr Bernhard Krismer, said: "Some of the animals
were completely clear, no single cell of the. "Others were reduced lugdunensis could reach patients and it may not prove. But new antibiotics are
desperately needed as doctors face the growing challenge of infections that
resist current drugs and could become untreatable.
'Pressure to eliminate' all the known causes of pathogens Fellow researcher Prof Andreas
Peschel said the body could be mined for new antibiotics."Lugdunin may be
the first example of such an antibiotic, we have started a screening
program," he said and he even believes that people could one day be
infected with genetically-modified bacteria to fight their infections. He argued: "By introducing the
lugdunin genes into a completely innocuous bacterial species we hope to develop
a new preventive concept of antibiotics that can eradicate pathogens."
Prof Kim Lewis and Dr Philip Strandwitz, from the antimicrobial discovery
centre at Northeastern University in the US, commented "It may seem
surprising that a member of the human microbiota - the community of bacteria
that inhabits the body - produces an antibiotic.
"However, the microbiota is
composed of more than a thousand species, many of which compete for space and
nutrients, and the selective pressure to eliminate bacterial neighbours is
high." Prof Colin Garner, the head of Antibiotic Research UK, told the
BBC: "Altering the balance of bacteria in our bodies through the
production of natural antibiotics could eventually be exploited to fight off
bacterial infections."It is possible that this
report will be the first of many demonstrating that bacteria in our bodies can
produce novel antibiotics with new chemical structures. "Alongside a
report that men with beards have fewer pathogens including MRSA on their faces
than clean-shaven men, it seems the paper identifying lugdunin should be viewed
alongside facial hair as a preventer of infection."