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Wednesday, February 27, 2013

Tissue Replacement.

The process for replacement tissue can be fast, to make remake and replace might be the future of medicine, in some future time and place as I hope people make the planetary jump although agents all odds. Maybe because of human colon takes the priority,  instead of a planetary colony. Now with tissue rejuvenation able to grow ears even some stage able to grow teeth has led these developmental techniques will keep the girls happy as there more prone to tooth loss due to childbirth, although this is a more complex process.
So as the teeth brake instead of a extraction them have a laboratory enamel crown plate with one own tissue cement even on a pre pay for a renewal teeth plan have them inspected for ware and tare, Professor Bonassar and colleagues started with a digitised 3D image of a human subject's ear. Breakthrough: A 3D printer in Weill Hall deposits cells encapsulated in a hydro gel that will develop into new ear tissue. The printer takes instructions from a file built from 3D scans of real human ears. They then used a 3D printer to assemble a mould based on the scan and poured in their 'living' collagen gel. Bio engineers have used 3D printing to achieve a breakthrough in prosthesis by creating the first artificial ears that look and act like real ones.A new study by researchers at Cornell University, New York, shows how prosthetic ears almost indistinguishable from natural ones can be 3D printed using gels made of living cells. Not only that but over a three-month period these flexible, artificial ears even grew their own cartilage to replace the collagen used to mould them. 'A bioengineered ear replacement like this would also help individuals who have lost part or all of their external ear in an accident or from cancer,' he said. Currently, replacement ears are usually constructed with materials that have an unnatural Styrofoam-like consistency.
Alternatively surgeons may sometimes build ears from a patent's harvested rib, but this option is challenging and painful for children, and the ears rarely look natural or perform well, said Dr Spector. New hope: Professor Lawrence Bonassar and colleagues collaborated with Weill Cornell Medical College physicians to create an artificial ear using 3D printing and inject-able molds 'This is such a win-win for both medicine and basic science, demonstrating what we can achieve when we work together,' said study author Lawrence Bonassar, associate professor of biomedical engineering.
The novel ear may be the solution surgeons have long wished for to help children born with ear deformity, said co-author Dr Jason Spector, professor of plastic surgery at Weill Cornell Medical College. A bionic hand which allows the recipient to feel ‘lifelike’ sensations is to be transplanted on to a patient’s arm for the first time. Until now, artificial limbs have been able to pick up brain signals destined for the absent hand and translate them into movements, but they could not give sensory feedback. The new hand, which is attached directly to the nervous system via electrodes clipped on to two of the arm’s main nerves, aims to restore a sense of touch in amputees. The electrodes will allow the recipient to control the hand using just their thoughts – and will also send signals back to the brain.  Scientists hope the breakthrough will pave the way  for a new generation of artificial limbs that more closely imitate real body parts by providing feeling and increased dexterity. This Cornell-developed, high-density gel is similar to the consistency of jelly when the mould is removed. The collagen serves as a scaffold upon which cartilage could grow.
Professor Bonassar added.'It takes half a day to design the mould, a day or so to print it, 30 minutes to inject the gel, and we can remove the ear 15 minutes later,' he said. 'We trim the ear and then let it culture for several days in nourishing cell culture media before it is implanted. 'The new process offers hope to thousands of children born with a congenital deformity called microtia.
The incidence of microtia, which is when the external ear is not fully developed, varies from almost 1 to more than 4 per 10,000 births each year. Many children born with microtia have an intact inner ear, but experience hearing loss due to the missing external structure. Dr Spector and Professor Bonassar have been collaborating on bio engineered human replacement parts since 2007.Professor Bonassar has also worked with Weill Cornell neurological surgeon Dr Roger Härtl on bio engineered disc replacements using some of the same techniques.
The researchers specifically work on replacement human structures that are primarily made of cartilage – joints, trachea, spine, nose – because cartilage does not need to be vascularised with a blood supply in order to survive. 'Using human cells, specifically those from the same patient, would reduce any possibility of rejection,' Dr Spector said. He added that the best time to implant a bio engineered ear on a child would be when they are about five or six years old. At that age, ears are 80 per cent of their adult size.If all safety and efficacy trials prove successful, it might be possible to try the first human implant of a Cornell bioengineering ear in as little as three years, Dr Spector said.

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